William J Murphy

1 of 3 Interdisciplinary Collaboratory for Enhancing Translational Therapeutics Utilizing Biologically, Immunologically, and Metabollically Relevant Models of Breast Cancer

Breast

Robert J Turesky

2-Amino-9H-pyrido[2,3-b]indole: a Potential Colorectal Carcinogen Formed in Tobac

Colorectum

Matthew L Freedman

4C and Genome Editing for Causal SNP and Gene Discovery at Cancer Risk Loci

Melanoma of skin All cancers but non-melanoma skin cancer

Shridar Ganesan

53BP1-Mediated Regulation of DNA Repair and Chemoresistance

Breast

Gerd P Pfeifer

5-hydroxymethylcytosine in Human Cancer

Leukaemia Brain, nervous system

Daniela Salvemini

A3AR Agonists to Prevent Chemotherapy-Induced Painful Peripheral Neuropathy

All cancers but non-melanoma skin cancer

Alex Kentsis

Aberrant activation of HGF/MET signaling as a therapeutic target in AML

Leukaemia

Zhihong Gong

Aberrant DNA methylation patterns of miRNAs and breast cancer racial disparities

Breast

Elizabeth Grimm

Aberrant Silencing of a Large Micro-RNA Cluster on Chromosome 14q32 and its Relation to Aberrant c-MET/n-RAS Signaling in Cutaneous Malignant Melanoma-Implications for Novel Therapeutic Approaches and Biomarkers

Melanoma of skin

Pathology

Anna R. Giuliano

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Oesophagus Lip, oral cavity

Ninh La-Beck

Abrogating Nanoparticle-induced Immunosuppression in Tumor Microenvironment

All cancers but non-melanoma skin cancer

Alastair Davies

A Cancer Stem Cell-Directed Therapy for Enzalutamide-Resistant Prostate Cancer

Prostate

Surgery / Surgical oncology

Shuji Ogino

Accelerating Transdisciplinary Epidemiology of Colorectal Cancer

Colorectum

John Bligh

Accelerating translational research through Cardiff University's Clinical Innovation pipeline

Melanoma of skin All cancers but non-melanoma skin cancer

Lingyin Li

A chemical biology approach towards understanding the anti-cancer innate immunity

All cancers but non-melanoma skin cancer

David E Goldgar

A Comprehensive Approach to Breast Cancer Susceptibility Across the Risk Spectrum

Breast

Christian Landry

A comprehensive genotype-phenotype map of a eukaryotic complexome

Melanoma of skin All cancers but non-melanoma skin cancer

Hisataka Kobayashi

Activatable Molecular Cancer Imaging Probe

All cancers but non-melanoma skin cancer

Peter Aplan

Activation of Proto-Oncogenes by Chromosomal Translocation

Leukaemia

Hematology and hematologic malignancies Pathology

Barbara H Jung

Activin Signaling and Regulation in the Colon

Colorectum

Kinam Park

Adaptable Polymer Micelles for Tumor Targeting

Prostate Breast

Sheena N Smith

Adenoviral delivery of protein-based therapeutics to the tumor microenvironment

Breast

Dmitry Temiakov

Administrative Supplement for R01 GM104231-01 Mechanisms of transcription initiation in mitochondria

Melanoma of skin All cancers but non-melanoma skin cancer

Terry Fry

Adoptive T cell Therapy for Pediatric Leukemia

Leukaemia

Pediatric oncology or childhood cancer

Erica K Sloan

Adrenergic Regulation of Tumor Inflammation and Metastatic Dissemination

Breast

Amanda G Paulovich

Advanced development of immuno-MRM technology to analyze archived cancer tissues

Melanoma of skin All cancers but non-melanoma skin cancer

Stephan Maier

Advanced Techniques For Rapid And Artifact-Resistant MR Diffusion Imaging

Prostate Brain, nervous system

Dale Wigley

A facility for in-house analysis and X-ray data collection of crystals with large subunit cells.

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Annalisa Carlucci

A Functional Genomic Screen of De-Ubiquitinating Enzymes Involved in Ovarian Cancer Progression

Ovary

Pathology

Eric Collisson

A Genetically Defined System to Identify Factors Essential for KRas Oncogenesis

Pancreas

Pathology

Peter Roy

A Genetic and Biochemical Analysis of the Novel Guidance Cue MADD-4

Melanoma of skin All cancers but non-melanoma skin cancer

Sarah Hughes

A Genetic Model for Neurofibromatosis Type II

Melanoma of skin All cancers but non-melanoma skin cancer

Nicholas Schuh

A genetic regulatory model of interleukin-17-mediated gut inflammation and immunity.

Colorectum

Brian Raught

A Global Ubiquitin-Proteasome System Map

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph Barchi

A Glycopeptide from Interstitial Cystitis Patients as a Novel Anticancer Lead

All cancers but non-melanoma skin cancer

Carl Hansen

A high-throughput single-cell technology for the function-based discovery of monoclonal antibody antagonists of G-protein coupled receptors in cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Casey Farquhar

AIDS International Training and Research Program

Kaposi sarcoma Colorectum Cervix uteri Brain, nervous system

Yuet Ming Rebecca Chin

Akt isoform-specific signaling in breast cancer metastasis

Breast

Jae H Kang

A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline

Melanoma of skin All cancers but non-melanoma skin cancer

Shakti H Ramkissoon

ALK signaling in CNS development, ischemic brain injury and gliomagenesis

Brain, nervous system

Terry Fry

ALL Immunobiology and the Bone Marrow Niche

Leukaemia

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Marie Bleakley

Allogeneic stem cell transplant with grafts depleted of naive T cells for leukemi

All cancers but non-melanoma skin cancer

Ronald S Rock

Allostery in myosins studied at the molecular level

All cancers but non-melanoma skin cancer

Valeri Vasioukhin

Alpha-Catenin in Regulation of Tissue Homeostasis and Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

John Tavis

Alpha Hydroxytropolones as HCC Preventatives

Liver and intrahepatic bile ducts

Pathology

Renato V Iozzo

Altered Proteoglycan Gene Expression and Cancer

Breast

Powel Brown

ALTERNATIVE DOSING OF EXEMESTANE IN POSTMENOPAUSAL WOMEN WITH STAGE 0-II ER-POSITIVE BREAST CANCER: A RANDOMIZED PRESURGICAL TRIAL

Breast

Vladimir Bogdanov

Alternatively Spliced Tissue Factor and Pathobiology of Pancreatic Cancer

Pancreas

Pathology

Mikel Garcia-Marcos

Alternative mechanisms of signaling via trimeric G proteins

Melanoma of skin All cancers but non-melanoma skin cancer

Zhiyuan Shen

Alternative Mechanisms to Inactivate p53 during Oncogenesis

Non-Melanoma skin cancer Breast Brain, nervous system

Zhiyuan Shen

Alternative Mechanisms to Inactivate p53 During Oncogenesis

Non-Melanoma skin cancer Breast Brain, nervous system

Jan Rainey

A mechanistic study of G-protein coupled receptor binding and activation by apelin.

Trachea, bronchus and lung Other pharynx Oesophagus Non-Hodgkin lymphoma Nasopharynx Liver and intrahepatic bile ducts Kidney, renal pelvis and ureter Kaposi sarcoma Hodgkin lymphoma Colorectum Cervix uteri

Humsa Venkatesh

A Mechanistic Understanding of Neuronal Activity Promotion of High-Grade Glioma Growth through Activity-Regulated Secretion of Neuroligin-3

Brain, nervous system

Kathleen Kelly Siebenlist

A Mitogen-induced G Protein-coupled Receptor

Thyroid

Pathology

Margaret A Goodell

A Mouse Model of DNMT3A-Associated Hematologic Malignancy

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

Scott Kopetz

AMPK Directs the Balance Between Mutant Kras and PI3K Signaling and Defines Molecular Subsets in Colorectal Cancer

Colorectum

Anna L Malkova

Amplification of risk resulting from mis-routing of double-strand break repair

All cancers but non-melanoma skin cancer

Powel Brown

A MULTICENTER PHASE II STUDY OF DOCOSAHEXAENOIC ACID IN PATIENTS WITH A HISTORY OF BREAST CANCER, PREMALIGNANT LESIONS, OR BENIGN BREAST DISEASE

Breast

Eric B. Haura

AN ACTIVE ROLE OF ADAPTOR PROTEINS IN TYROSINE KINASE INHIBITOR RESISTANCE

Trachea, bronchus and lung

Junjie Chen

Analysis of BRCA1 function in DNA Repair

Breast

Ralph Scully

Analysis of BRCA1 Recombination Functions

Breast

Tim Greten

Analysis of Cancer-Related Immune Suppressor Mechanisms in Mice

Breast

Carl D Novina

Analysis of cap-dependent translational repression by microRNAs in oncogenisis

Melanoma of skin All cancers but non-melanoma skin cancer

Yamini Dalal

Analysis of Centromere Identity and Structure in Human Cells

All cancers but non-melanoma skin cancer

Habtom Ressom

Analysis of Lc-MS Data to Identify Peptide and Glycan Biomarkers for Hepatocellular Carcinoma.

Liver and intrahepatic bile ducts

Pathology

Charlotte Kuperwasser

Analysis of the cellular and molecular determinants of the human breast hierarchy

Breast

Pathology

Antonio J Giraldez

Analysis of the gene networks regulating the maternal to zygotic transition

All cancers but non-melanoma skin cancer

Stephen J Elledge

Analysis of the Mammalian DNA Damage Response

Breast

Charles Roberts

Analysis of the role of the SWI/SNF complex in tumor suppression

Melanoma of skin All cancers but non-melanoma skin cancer

Richard Hodes

Analysis of the T Cell Repertoire

Thymus

Radiation Oncology

John J. Krolewski

An Androgen-Regulated Cytokine Network Controls Prostate Apoptosis.

Prostate

Pathology

Richard L Haspel

A National Curriculum in Cancer Genomics for Pathology Residents

Melanoma of skin All cancers but non-melanoma skin cancer

Pathology

Steven P. Balk

Androgen Receptor Action in Castration Resistant Prostate Cancer

Prostate

Kevin Hughes Kensler

Androgen receptor expression and signaling and breast cancer risk and progression

Breast

Zijie Sun

A new regulator for Wnt/beta-catenin signaling and prostate tumorigenesis

Prostate

Zijie Sun

A New Regulator for Wnt/beta-catenin Signaling and Prostate Tumorigenesis

Prostate

Pathology

Giovanna Tosato

Angiogenesis and Tumor Growth

Trachea, bronchus and lung Kaposi sarcoma

Peter Choyke

Angiogenesis Imaging

Breast Brain, nervous system

Paul J. Anderson

Angiogenin-Induced RNA Cleavage in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Oliver Smithies

Animal Models for Studying the Genetics of Hypertension

All cancers but non-melanoma skin cancer

Laura A Johnston

An innate system for detection of aberrant tissue growth

All cancers but non-melanoma skin cancer

Myron D Gross

An Integrated Study of Mitochondrial Pathways in Colorectal Cancer

Colorectum

Helen Tanton

An investigation into the role of ATPase Inhibitory Factor 1 in pancreatic cancer

All cancers but non-melanoma skin cancer

Richard J Gilbertson

An Investigation of Radial Glia as the Source of Ependymoma Stem Cells

Brain, nervous system

Sarit Smolikove

An organismal approach to dissecting the mechanism of DSB repair pathway choice

All cancers but non-melanoma skin cancer

Genaro R. Villa

A Novel Approach to Treating Glioblastoma through Activation of the Liver X Recep

Brain, nervous system

Nikolaos Parisis

A Novel Histone H3 Phosphorylation that Regulates Genome Integrity

All cancers but non-melanoma skin cancer

Maike Sander

A novel mouse model to identify biomarkers of IPMN formation and progression

Pancreas

Pathology

Ankit Sinha

A novel N-glyco-proteomics driven strategy to identify tumour secreted proteins using patient-derived xenografts.

Ovary

Lixin Wan

A Novel Oncogenic Role for Cdc20 Implications in Adult T Cell Leukemia Treatment

Leukaemia

Barbara M Mueller

A Novel Plasminogen Receptor in Breast Cancer

Breast

Jenny Hsu

A novel role for E2F4 as a transcriptional activator and a cell cycle driver

Melanoma of skin All cancers but non-melanoma skin cancer

Prabodhika Mallikaratchy

Antibody Guided Cell-SELEX Technology

All cancers but non-melanoma skin cancer

James D Marks

Antibody Research Technology Center

Sarcoma Nasopharynx Kidney, renal pelvis and ureter All cancers but non-melanoma skin cancer

Dimiter Dimitrov

Antibody therapeutics against biodefense-related diseases

Brain, nervous system

Scott H Kaufmann

Anticancer Drug-Induced BH3-only Protein.Bak Interactions

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Brian A Cobb

Antigenic Carbohydrate Structure, Function, and Specificity

All cancers but non-melanoma skin cancer

Jay Berzofsky

Antigen-specific T-cell Activation, Application to Vaccines for Cancer and AIDS

Prostate Breast

John Digiovanni

Anti-Promoting Effects of Triterpenes Alone or Combined with Other Phytochemicals

Melanoma of skin Non-Melanoma skin cancer

Gary Rosenberg

AP 1. Biodiversity

Pancreas Brain, nervous system

Gisela P Concepcion

AP 3. Chemistry and Drug Discovery

Pancreas Brain, nervous system

Eric W Schmidt

AP 4. Drug Screening and Pharmacology

Pancreas Brain, nervous system

Gobel Verena

Apical membrane modeling in tubulogenesis

All cancers but non-melanoma skin cancer

Scott Atwood

aPKC function in Hedgehog signaling and basal cell carcinoma

All cancers but non-melanoma skin cancer

Pathology

Richard K. Wilson

A Platform for Large-Scale Genomic Discovery

All cancers but non-melanoma skin cancer

Sharad Kumar

Apoptosomes Structure and Procaspase Activation

All cancers but non-melanoma skin cancer

Natalie Fox

A portrait of functional associations of DNA and RNA in prostate cancer

Prostate

Robert A Gatenby

Application of Evolutionary Principles to Maintain Cancer Control (PQ21)

Breast

Paul L Fox

A protein-directed RNA switch that regulates translation

All cancers but non-melanoma skin cancer

Elliot Chaikof

A PSGL-1 Glycopeptide Mimetic for Treatment of Venous Thromboembolism

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph H Antin

A Randomized Trial of Tac/MTX/bortezomib vs Tac/MTXplacebo in Allogeneic HSCT

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

David Fitch

Architecture of a Genetic Network Governing Morphogenesis

All cancers but non-melanoma skin cancer

Scott M Dehm

AR Gene Rearrangements and AR Signaling in Prostate Cancer

Prostate

Pathology

Jun J Yang

ARID5B and Disparities of Childhood Leukemia

Leukaemia

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Giovanna Tosato

A Role for KSHV in the Pathogenesis of Malignancies

Trachea, bronchus and lung Kaposi sarcoma Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Myron Steve Ignatius

A role for notch in self renewal in embryonal rhabdomyosarcoma

Sarcoma

Investigator from Spanish National Research Council

Artificial evolution of a novel multifunctional human polymerase

Melanoma of skin All cancers but non-melanoma skin cancer

Elaine Dunleavy

Assembly and function of Drosophila melanogaster centromeric chromatin during meiosis and development.

Melanoma of skin All cancers but non-melanoma skin cancer

William Muller

Assess the relative contribution of particular signaling molecules to each stage of breast cancer progression (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Jian-Yue Jin

A Synchronized Moving Grid (SMOG) System to Improve CBCT for IGRT and ART

All cancers but non-melanoma skin cancer

Tina Yuan

A systematic dissection of oncogenic KRAS signaling for target identification and therapeutic development

Melanoma of skin All cancers but non-melanoma skin cancer

Anne-Claude Gingras

A systems approach towards the therapeutic modulation of the acetylome

Melanoma of skin All cancers but non-melanoma skin cancer

Gerald R. Crabtree

ATP-Dependent Chromatin Remodeling in Human Malignancy

Melanoma of skin All cancers but non-melanoma skin cancer

James Kochenderfer

Autologous T cells Transduced with an Anti-CD19 Chimeric Antigen Receptor

Leukaemia

Hematology and hematologic malignancies

Leslie M Shaw

Autophagy-independent function of Beclin 1 in Breast Cancer

Breast

Angela Parrish

Axin-induced Wnt signaling in mouse embryogenesis and Wnt-related cancers

Colorectum Breast

Keila Enitt Torres

Axl receptor signaling in MPNST; potential node for therapy

Sarcoma

Joseph Culotti

Axon guidance and cell migration mechanisms in C. elegans

Melanoma of skin All cancers but non-melanoma skin cancer

Susan Gottesman

Bacterial Functions Involved in Cell Growth Control

All cancers but non-melanoma skin cancer

Kevin Michael Haigis

Basic and Translational studies of Ras-mutant colorectal cancer

Colorectum

Radoslav Goldman

Basic Cancer Research in Cancer Health Disparities

Prostate

Pathology

Aimin Jiang

b-catenin in vaccine-induced anti-tumor CD8 T cell immunity

Melanoma of skin All cancers but non-melanoma skin cancer

Clark W Distelhorst

Bcl-2 Function on the Endoplasmic Reticulum

Non-Hodgkin lymphoma Multiple myeloma and immunoproliferative diseases Leukaemia

Hematology and hematologic malignancies Pathology

Tomasz Skorski

BCR/ABL-PI-3k-ROS pathway induce genomic instability ....

Leukaemia

Hematology and hematologic malignancies Pathology

Anthony E Oro

BEG4/MIM Function in Epithelial Neoplasia

Non-Melanoma skin cancer

Paul B. Jacobsen

Behavioral Oncology Education & Career Development

Melanoma of skin All cancers but non-melanoma skin cancer

Brian K. Kobilka

Beta2 Adrenoceptor Structure and Mechanism of Activation

Melanoma of skin All cancers but non-melanoma skin cancer

John Nicholas

BH3-only Protein Targeting by HHV-8

Non-Hodgkin lymphoma Kaposi sarcoma Hodgkin lymphoma

Pathology

Suresh Ambudkar

Biochemical Analysis of Multidrug Resistance-linked Transport Proteins

Leukaemia

Hematology and hematologic malignancies Pathology

Lawrence Samelson

Biochemical Basis of T Cell Activation

Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Michael Maurizi

Biochemistry of Energy-Dependent (Intracellular) Protein Degradation

All cancers but non-melanoma skin cancer

Arash Hatefi

Bioengineering a Safe and Efficient Vector Technology for Stem Cell Transfection

Melanoma of skin All cancers but non-melanoma skin cancer

Mikhail Shapiro

Biogenic Gas Nanostructures As Molecular Imaging Reporters For Ultrasound

Melanoma of skin All cancers but non-melanoma skin cancer

Giovanni Luigi Parmigiani

Bioinformatics Tools for Genomic Analysis of Tumor and Stromal Pathways in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Karl Munger

Biological Activity of HPV E7 in Human Epithelial Cells

Cervix uteri

Pathology

Channing J Der

Biological Activity of Ras Oncogenes

Pancreas

Pathology

Gordon B. Mills

Biological annotation of TCGA data

Melanoma of skin All cancers but non-melanoma skin cancer