University of Toronto

Lewis Kay

CRC Tier 1 - Develop new Nuclear Magnetic Resonance Spectroscopy based techniques for relating molecular motions to function

Melanoma of skin All cancers but non-melanoma skin cancer

John Dick

Identify and understand the differences between normal HSCs and LSCs (CANADA RESEARCH CHAIRHOLDER)

Leukaemia

Jason Moffat

CRC Tier 2 - Identify novel cancer cell vulnerabilities

Melanoma of skin All cancers but non-melanoma skin cancer

Benjamin Neel

CRC Tier 1 - Treatments for RASopathies and cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Tak Mak

CRC Tier 1 - Determining why mutations of the metabolic enzyme isocitrate dehydrogenase cause leukemias and brain cancers

Leukaemia Brain, nervous system

Patrick O'Donoghue

CRC Tier 2 - Protein modifications Signalling

Melanoma of skin All cancers but non-melanoma skin cancer

Mitsuhiko Ikura

Protein structure and protein interactions (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Linda Penn

CRC Tier 1 - Cancer Biology

Melanoma of skin All cancers but non-melanoma skin cancer

Laurence Pelletier

CRC Tier 1 - Understand how centrosome duplicate, grow and participate in the formation of mitotic spindles and cilia

Melanoma of skin All cancers but non-melanoma skin cancer

Pathology

Igor Jurisica

CRC Tier 1 - Tools and resources for systematically discovering clinically-relevant biomarkers of cancer

Trachea, bronchus and lung Prostate Pancreas Ovary Other pharynx Oesophagus Nasopharynx Melanoma of skin Lip, oral cavity Leukaemia Larynx Breast

Daniel Durocher

CRC Tier 1 - DNA damage

Melanoma of skin All cancers but non-melanoma skin cancer

Stephane Angers

Wnt proteins signalling pathways (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Alexander Palazzo

Dissecting the Molecular Mechanisms of the Alternative Nuclear Export and Endoplasmic Reticulum Targeting of Secretory mRNAs.

Melanoma of skin All cancers but non-melanoma skin cancer

Pathology

Alexander Little

Non-genomic actions of Rev-erb

Melanoma of skin All cancers but non-melanoma skin cancer

Alberto Martin

The mechanisms of secondary antibody diversification processes

Non-Hodgkin lymphoma Hodgkin lymphoma

Alberto Martin

The impact of the gut microbiome and environment on the development of colorectal cancer

Colorectum

Pathology

Alan Davidson

In Vitro, In Vivo, and Bioinformatic Studies on the Function of SH3 Domains

Melanoma of skin All cancers but non-melanoma skin cancer

A. K. M. Nur-Ur Rahman

Defining the role of T cell metabolism in HIV-induced chronic immune activation and immune dysfunction.

Melanoma of skin All cancers but non-melanoma skin cancer

Tracey Galloway

A qualitative study of the experience of cancer and death from cancer among Inuit residents of Nunavut using Indigenous and Western methodologies

Melanoma of skin All cancers but non-melanoma skin cancer

Natalie Fox

A portrait of functional associations of DNA and RNA in prostate cancer

Prostate

Javaid Iqbal

A population based study of the impact of pregnancy on breast cancer mortality in women in Ontario

Breast

Sean Mccurdy

A novel use of E2f and Cdk inhibitors to prevent RB1-null tumors in genetically engineered models of retinoblastoma and other cancers

Brain, nervous system

Pediatric oncology or childhood cancer

Nicholas Schuh

A genetic regulatory model of interleukin-17-mediated gut inflammation and immunity.

Colorectum

Peter Roy

A Genetic and Biochemical Analysis of the Novel Guidance Cue MADD-4

Melanoma of skin All cancers but non-melanoma skin cancer

Elizabeth Willis

A Chemical Biology Approach to the Study of Polysialic Acid in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Jason Mills

Gastric Cancer in Nicaragua

Stomach

Pathology

Anita Kinney

Cancer Prevention in Women with a BRCA Mutation: A Follow-up Genetic Counselling Intervention

Ovary Breast

Peter Aplan

Collaborative Pathways that Lead to Leukemia – Rockville

Leukaemia

Hematology and hematologic malignancies Pathology

Kosj Yamoah

Genomic Biomarker for Aggressive Prostate Cancer in Men of African Descent

Prostate

Pathology

Jeffrey Rubin

Wnt Signaling and Secreted Frizzled-Related Proteins

All cancers but non-melanoma skin cancer

Gretchen Gierach

Ultrasound Study of Tamoxifen

Breast

Yun-Xing Wang

SAXS Core

All cancers but non-melanoma skin cancer

Deborah Morrison

Role of Protein Scaffolds in RTK/Ras-Dependent Signal Transduction

Trachea, bronchus and lung All cancers but non-melanoma skin cancer

Sharon Savage

Retrospective Study of Genetic Risk Factors for Osteosarcoma

All cancers but non-melanoma skin cancer

Deborah Morrison

Regulation of Ras-Dependent Signal Transduction Pathways

Trachea, bronchus and lung Thyroid Pancreas Ovary Melanoma of skin Colorectum

Dan Sullivan

Princess Margaret Phase I Consortium

All cancers but non-melanoma skin cancer

Demetrius Albanes

Pooling Project of Prospective Studies of Diet and Cancer

Trachea, bronchus and lung Testis Stomach Prostate Pancreas Oesophagus Non-Hodgkin lymphoma Liver and intrahepatic bile ducts Leukaemia Larynx Kidney, renal pelvis and ureter Colorectum Brain, nervous system Bladder

Munira Basrai

Molecular Determinants of Chromosome Transmission and Cell Cycle Regulation

Trachea, bronchus and lung Colorectum Breast

Scott Gilbert

Longitudinal Surveillance (Total Cancer Care)

All cancers but non-melanoma skin cancer

Sharon Savage

Li-Fraumeni Syndrome Studies

All cancers but non-melanoma skin cancer

Blanche Alter

Inherited Bone Marrow Failure Syndromes study - international laboratory collaborators.

Trachea, bronchus and lung Pancreas Other pharynx Oesophagus Nasopharynx Liver and intrahepatic bile ducts Lip, oral cavity Leukaemia Larynx Cervix uteri Breast Brain, nervous system

Charles Vinson

Gene Regulation and Function: The B-ZIP Proteins

All cancers but non-melanoma skin cancer