NCI is collaborating with investigators from China (Chinese Academy of Medical Sciences and the Shanghai Cancer Institute), India, Japan, Korea, Malaysia, Singapore, Taiwan, and other countries in the Asia Cohort Consortium (ACC), which is led by the Fred Hutchinson Cancer Research Center. The ACC is a collaborative effort seeking to understand the relationship between genetics, environmental exposures, and the etiology of disease through the establishment of a cohort of at least one million healthy people around the world. These participants will be followed over time to various disease endpoints, including cancer. The collaboration also involves seeking partners among existing cohorts across Asia to facilitate the exploration of specific research questions that need more immediate answers.