The Burkitt Lymphoma Trials network (BLTN), collaborates with U.S. National Cancer Institute, to study Burkitt Lymphoma in children in various international settings. In its approach BLTN pursues the principles of scientific excellence, international cooperation and the full and open exchange of scientific information relevant to treatment and prevention. The collaboration will allow for efficient studies of Burkitt Lymphoma, prevention, translation and treatment in children at seven sites throughout Sub-Saharan Africa and Latin America.