Dr. Werbowetski-Ogilvies research focuses on using human stem cells to study the most common and highly invasive malignant brain tumours: glioblastoma multiforme (GBM) and medulloblastoma. Even after treatment, these tumours typically recur leading to poor clinical outcome. Researchers are also faced with the challenge of identifying brain tumours in their early stages. Dr. Werbowetski-Ogilvies laboratory is addressing these issues using human embryonic stem cells and their cancer-like derivatives to identify proteins that mark the early events during brain tumorigenesis. Dr. Werbowetski-Ogilvie is also further characterizing invasive brain tumour cells to identify new biomarkers that can better predict clinical outcome.