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Structural and Functional Studies of Tumor Suppressor Proteins PALB2 and BRCA2

Sergey Korolev

1 Collaborator(s)

The goal is to reveal mechanism of proteins function in DNA repair and cancer development.

Related projects

William C Hahn

Regulation and function of IKKe in breast cancer initiation and maintenance

Breast

Pathology

Samuel Aparicio

PP2a protein serine/threonine phosphatase mutations in cancer: functional consequences and clinical relevance

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Peter Sicinski

Cyclin-Dependent Kinases in Oncogenesis

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Stephen J Elledge

Analysis of the Mammalian DNA Damage Response

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Frank Jirik

Combining development of transgenic animals with the application of advanced phenotyping technologies (CANADA RESEARCH CHAIRHOLDER)

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Roger D Kamm

Microfluidic 3D Assays for Metastatic Cancer

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Naoto Ueno

Understanding EGFR's Role in TNBC by an Animal Model

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Elizabeth Mittendorf

Immunologic Aspects of Triple Negative Breast Cancer and the Effects of Neoadjuvant Systemic Therapy

Breast

Dario Marchetti

Functional characterization of brain-colonizing breast cancer CTC subsets

Breast