BC Cancer Agency
BCCA

Brad Nelson

Toward personalized immunotherapy: identifying tumour-specific factors that dictate the response of spontaneous mammary cancers to T cells

Breast

Spencer Martin

Development of personalized vaccines targeting tumour-specific mutations

Melanoma of skin All cancers but non-melanoma skin cancer

Wan Lam

Understanding the mechanisms of lung cancer development in never smokers

Trachea, bronchus and lung

David Twa

The significance of recurrent translocations involving programmed death ligands in non-Hodgkin lymphomas

Non-Hodgkin lymphoma

Shoukat Dedhar

The Role of Tumor Microenvironment in Cancer Progression: Identification and Therapeutic Intervention of Novel Targets

Melanoma of skin All cancers but non-melanoma skin cancer

Isabella Tai

The Role of SPARC in Cancer Therapy Sensitization

Melanoma of skin All cancers but non-melanoma skin cancer

Angel Chia-Yu Yu

The role of NPM1 in apoptosis resistance in colorectal cancer

Colorectum

Poul Sorensen

The Hace1 tumour suppressor--a novel regulator of the oxidative stress response

Kidney, renal pelvis and ureter

Pediatric oncology or childhood cancer

Stephen Choi

Targeting monocarboxylate transporter 4 (MCT4) for treatment of castration resistant prostate cancer (CRPC)

Prostate

Joseph Lau

Targeting Carbonic Anhydrase IX and Hypoxia for the Diagnosis and Treatment of Aggressive Breast Cancers

Breast

Shoukat Dedhar

Targeting Carbonic Anhydrase IX and Hypoxia for the diagnosis and treatment of aggresive breast cancers

Breast

Gregg Morin

Recurrent Somatic DICER1 Mutations: Functional Implication and Role in Oncogenesis

Melanoma of skin All cancers but non-melanoma skin cancer

Jithendra Gunawardana

Recurrent IL4R mutations in Primary Mediastinal Large B Cell Lymphoma

Non-Hodgkin lymphoma Hodgkin lymphoma

Calum Macaulay

Real-Time In Vivo Oral Pathology for Clinical Decision Making

Lip, oral cavity

Pathology

Mary Mcbride

Phase-Specific and Lifetime Medical Costs of Care for Childhood Cancer in British Columbia and Ontario

Melanoma of skin All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Yuzhuo Wang

Next generation patient-derived, genetically-defined prostate cancer xenograft models for anti- cancer drug development

Prostate

Yuzhuo Wang

Next generation patient-derived, genetically-defined kidney and bladder cancer xenograft models for anti-cancer drug development

Kidney, renal pelvis and ureter Bladder

Greg Stewart

New mechanisms driving non-small cell lung cancer

Trachea, bronchus and lung

Calum Macaulay

Multi-Scale Tissue System's Biology approach to Identify Lethal Prostate Cancer

Prostate

Pathology

Catherine Enfield

MicroRNAs as modulators of lung cancer targeted therapy and novel predictors of drug response

Trachea, bronchus and lung

Reka Pataky

Methods for the economic evaluation of personalized medicine: a case study in advanced colorectal cancer

Colorectum

Samuel Aparicio

Linking clonal genomes to tumour evolution and therapeutics

Melanoma of skin All cancers but non-melanoma skin cancer

Haishan Zeng

Integrated In Vivo Multiphoton Microscopy and Confocal Raman Spectroscopy for Skin Cancer Detection and Evaluation

Melanoma of skin Non-Melanoma skin cancer

Marcel Bally

Identifying Cytoprotective Responses Triggered Following Initial Exposure to Targeted Therapy: Defining Improved Treatment Strategies for Patients with HER-2 Positive Breast Cancer

Breast

Hanyang Lin

Identification of new microRNA biomarkers and candidate target genes in primitive CML cells using global comparative RNA analyses

Leukaemia

Helen Mctaggart-Cowan

General Public's Perception of a Quality-adjusted Life Year in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Marco Marra

Exploring the relationship between the genome and the epigenome in cancers

Melanoma of skin All cancers but non-melanoma skin cancer

Shoukat Dedhar

Development of therapeutic antibodies targeting carbonic anhydrase IX (CAIX)

Breast

Fang Wang

Defining the role of human isomiR-181a in myelodysplastic syndromes

Melanoma of skin All cancers but non-melanoma skin cancer

Reka Pataky

Comparing five-year and lifetime costs of cancer care in British Columbia and Ontario: phase-based costing with linked administrative data in two Canadian provinces

Melanoma of skin All cancers but non-melanoma skin cancer

Wan Lam

An integrative approach to understand lung cancer development in smokers and non-smokers

Trachea, bronchus and lung

Pathology

Peter Stirling

Understanding and exploiting genome instability in cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Robert Kridel

The pathogenic role of tumor-associated macrophages in Hodgkin lymphoma

Hodgkin lymphoma

Pathology

David Huntsman

The Genetics of Hereditary Upper Gastrointestinal Cancers: Beyond CDH1 Germline Mutations

Stomach Pancreas Oesophagus Colorectum

Pathology

Svetlana Bortnik

The effects of autophagy knockdown in breast cancer cells using in vivo xenograft models

Breast

Sohrab Shah

The clonal dynamics of ovarian cancers: phylogenetic models of chemosensitivity and resistance

Ovary

Pathology

Poul Sorensen

Targeting the tumour cell stress response in high-risk childhood cancers

Melanoma of skin All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Xiaoyan Jiang

Targeting Drug-Insensitive CML Stem Cells with Combination Therapy of New ABL and PP2A Inhibitors

Leukaemia

Andrew Roth

Studying The Evolution Of Cancer Genomes

Melanoma of skin All cancers but non-melanoma skin cancer

Scott Tyldesley

Strategic configuration of cancer care services based on clinical, demographic and geographic considerations

Melanoma of skin All cancers but non-melanoma skin cancer

Christian Steidl

Somatic mutations in the JAK-STAT signaling pathway in primary mediastinal large B cell lymphoma

Non-Hodgkin lymphoma Hodgkin lymphoma

Linda Ya-Ting Chang

Role of innate immune signaling in myelodysplastic syndromes

Leukaemia