Approximately 15-year collaboration in which I lead aspects and participate in aspects of research to identify tumor initiating cells in neuroblastoma and assess role and biologic impact of trk gene expression in neuroblastoma tumors. Lavoie JF et al J. Biol. Chem, 2006 Jaboin J, et al Cancer Res., 2002 Matsumoto et al Cancer Res, 1985 Kaplan et al Neuron, 1992 Most recently we have collaborted on the identification of BM-derived neuroblastoma tumor initiating cells Hansford et al Cancer Research 2007